Dr. SANKARASUBRAMANIAN JAGADESAN

Paper publications

• Veerappa A, Patel JC, Shakyawar S, Jagadesan S, Guda C (2025) scAED: a framework for mapping the enhancer state at single-cell resolution.  Briefings in Bioinformatics. 26 (6): bbaf646. 
• Jagadesan S, Guda C (2025) ScRDAVis: An R shiny application for single-cell transcriptome data analysis and visualization. PLoS Computational Biology. 21(11): e1013721.
• Bajpai P, Ghandour F, Jain E, Memon R, Patel CR, Karthikeyan SK, Jagadesan S, Guda B, Afaq F, Elkholy A, Varambally S, Manne U, Diffalha SA (2025) Defining molecular signatures of the solid/pseudopapillary and pseudoglandular patterns in so-called "solid-tubulocystic intrahepatic cholangiocarcinoma vs. NIPBL::NACC1 fusion hepatic carcinoma". Pathology - Research and Practice. 270:155962. 
• Jagadesan S, Guda C. (2025) MetaDAVis: An R shiny application for metagenomic data analysis and visualization. PLoS ONE. 20(4): e0319949.  
• Flores A, Nguyen N.M, Devanaboyina M, Sanketh M, Athota P, Jagadesan S, Guda C, Yelamanchili SV, Pendyala G. (2024) Neurobehavioral Characterization of Perinatal Oxycodone-Exposed Offspring in Early Adolescence. J Neuroimmune Pharmacol. 19: 29.  
• Pendyala VV, Pribil S, Schaal V, Sharma K, Jagadesan S, Yu L, Kumar V, Guda C, Gao L (2023)  Effects of Acute and Chronic Gabapentin Treatment on Cardiovascular Function of Rats. Cells. 12(23):2705.
• Athota P, Nguyen NM, Schaal VL, Jagadesan S, Guda C, Yelamanchili SV, Pendyala G. (2023) Novel RNA-Seq Signatures Post-Methamphetamine and Oxycodone Use in a Model of HIV-Associated Neurocognitive Disorders. Viruses. 15(9):1948. 
• Jagadesan S, Mondal P, Carlson MA, Guda C (2023) Evaluation of Five Mammalian Models for Human Disease Research Using Genomic and Bioinformatic Approaches. Biomedicines. 11(8):2197. 
• Yadav SK, Ahmad R, Moshfegh CM, Sankarasubramanian J, Joshi V, Elkhatib S.K, Chhonker YS, Murry DJ, Talmon GA, Guda C, Case A, Singh AB. (2023) Repeated Social Defeat Stress induces an Inflammatory Gut Milieu by altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis. Biological Psychiatry Global Open Science. 3(4):824-836. 
• Nguyen NM, Meyer D, Meyer L, Chand S, Jagadesan S, Miravite M, Guda C, Yelamanchili SV, Pendyala G. (2023) Identification of YWHAH as a Novel Brain-Derived Extracellular Vesicle Marker Post Long-Term Midazolam Exposure during Early Development. Cells. 12(6):966. 
• Bhat A, Abu R, Jagadesan S, Vellichirammal NN, Pendyala VV, Yu L, Rudebush TL, Guda C, Zucker IH, Kumar V, Gao L. (2023) Quantitative Proteomics Identifies Novel Nrf2-Mediated Adaptative Signaling Pathways in Skeletal Muscle Following Exercise Training. Antioxidants. 12(1):151. 
• Liu B, Kong Y, Shi W, Kuss M, Liao K, Hu G, Xiao P, Jagadesan S, Guda C, Wang X, Lei Y, Duan B. (2021) Exosomes Derived from Differentiated Human ADMSC with the Schwann Cell Phenotype Modulate Peripheral Nerve-Related Cellular Functions. Bioactive Materials. 14: 61-75. 
• Arumugam M, Sundararaju S, Jagadesan S, Gunasekaran P, Rajendhran J (2021) Metagenomic Analysis of Microbial Community Affiliated with Termitarium Reveals High Lignocellulolytic Potential. Current Microbiology.78(4):1551-1565. 
• Ramakrishnan V, Marialouis XA, Sankarasubramanian J, Santhanam A, Balakrishnan AS (2021) Whole Genomic analysis of a clinical isolate of Uropathogenic Escherichia coli strain of Sequence Type - 101 carrying the drug resistance NDM-7 in IncX3 plasmid. Bioinformation. 17(1), 126-131. 
• Odegaard KE, Schaal VL, Clark AR, Koul S, Sankarasubramanian J, Xia Z, Mellon M, Uberti M, Liu Y, Stothert A, Van Hook M, Wang H, Guda C, Lisco SJ, Pendyala G, Yelamanchili SV. (2021) A Holistic Systems Approach to Characterize the Impact of Pre- and Post-natal Oxycodone Exposure on Neurodevelopment and Behavior. Frontiers in Cell and Developmental Biology. 8:619199. 
• Sankarasubramanian J, Ahmad R, Singh AP, Guda C. (2020) Gut Microbiota and Metabolic Specificity in Ulcerative Colitis and Crohn's Disease. Frontiers in Medicine. 7, 606298. 
• Odegaard KE, Schaal VL, Clark AR, Koul S, Gowen A, Sankarasubramanian J, Xiao P, Guda C, Lisco SJ, Yelamanchili SV, Pendyala G. (2020) Characterization of the intergenerational impact of in utero and postnatal oxycodone exposure. Translational Psychiatry. 10, 329 
• Sujitha S, Vishnu US, Karthikeyan R, Sankarasubramanian J, Gunasekaran P, Rajendhran J (2019) Genome Investigation of a Cariogenic Pathogen with Implications in Cardiovascular Diseases. Indian Journal of Microbiology. 1-9. 
• Sahay S, Shome R, Sankarasubramanian J, Vishnu US, Prajapati A, Natesan K, Shome BR, Rahman H, Rajendhran J (2018) Genome sequence analysis of the Indian strain Mannheimia haemolytica serotype A2 from ovine pneumonic pasteurellosis. Annals of Microbiology. 1–10. 
• Somvanshi V, Dubay B, Kushwah J, Rammoorthy S, Vishnu US, Sankarasubramanian J, Rajendhran J, Rao U (2018) Draft genome for five Photorhabdus bacterial symbionts of entomopathogenic Heterorhabditis nematodes from India. Microbiology Resource Announcements. 8, e01404-18. 
• Sankarasubramanian J, Vishnu US, Gunasekaran P, Rajendhran J (2018) Development and evaluation of a core genome multilocus sequence typing (cgMLST) scheme for Brucella spp. Infection, Genetics and Evolution. 67, 38-43. 
• Sahay S, Shome R, Sankarasubramanian J, Vishnu US, Prajapati A, Natesan K, Shome BR, Rahman H, Rajendhran J (2018) Insights into the genome sequence of ovine Pasteurella multocida type A strain associated with pneumonic pasteurellosis. Small Ruminant Research. 169, 167-175 
• Sankarasubramanian J, Pavithra KB, Kavitha B (2018) Information Resource: Database on Indian Earthworm. Enliven: Bioinformatics. 4(2), 001. 
• Sankarasubramanian J, Vishnu US, Gunasekaran P, Rajendhran J (2017) Identification of genetic variants of Brucella spp. through genome-wide association studies. Infection, Genetics and Evolution. 56, 92-98. 
• Vishnu US, Sankarasubramanian J, Gunasekaran P, Rajendhran J (2017) Identification of potential antigens from non-classically secreted proteins and designing novel multitope peptide vaccine candidate against Brucella melitensis through reverse vaccinology and immunoinformatics approach. Infection, Genetics and Evolution. 55, 151-158. 
• Sankarasubramanian J, Vishnu US, Abdul Khader L.K.M, Sridhar J, Gunasekaran P, Rajendhran J (2016) BrucellaBase: Genome information resource. Infection, Genetics and Evolution. 43, 38-42. 
• Sankarasubramanian J, Vishnu US, Gunasekaran P, Rajendhran J (2016) A genome-wide SNP-based phylogenetic analysis distinguishes different biovars of Brucella suis. Infection, Genetics and Evolution. 41, 213-217. 
• Vishnu US, Sankarasubramanian J, Sridhar J, Gunasekaran P, Rajendhran J (2016) Omics of Brucella: Species-specific sRNA-mediated gene ontology regulatory networks identified by computational biology. OMICS: A Journal of Integrative Biology. 20(6), 375-85. 
• Rajeswari Shome, Natesan Krithiga, Padmashree B Shankaranarayana, Sankarasubramanian Jegadesan, Vishnu Udayakumar S, Bibek Ranjan Shome, Girin Kumar Saikia, Narendra Kumar Sharma, Harshad Chauhan, Bharat Singh Chandel, Rajendhran Jeyaprakash, Habibur Rahman (2016) Genotyping of Indian antigenic, vaccine, and field Brucella spp. using multilocus sequence typing. Journal of Infection in Developing Countries. 10(3), 237-244. 
• Sankarasubramanian J, Vishnu US, Dinakaran V, Sridhar J, Gunasekaran P, Rajendhran J (2016) Computational prediction of secretion systems and secretomes of Brucella: identification of novel type IV effectors and their interaction with the host. Molecular BioSystems. 12(1), 178-90. 
• Chaudhuri P, Goswami T TK, Lalsiamthara J, Kaur G, Vishnu US, Sankarasubramanian J, Gunasekaran P, Rajendhran J. 2015. Draft genome sequence of the intermediate rough vaccine strain Brucella abortus S19Δper mutant. Genome Announcements. 3(6), e01336-15. 
• Vishnu US, Sankarasubramanian J, Gunasekaran P, Rajendhran J (2016) Identification of OtpR regulated sRNAs in Brucella melitensis expressed under acidic stress and their roles in pathogenesis and metabolism. Comparative Immunology, Microbiology and Infectious Diseases. 50, 40-47. 
• Vishnu US, Sankarasubramanian J, Sridhar J, Gunasekaran P, Rajendhran J (2015) Identification of Recombination and Positively Selected Genes in Brucella. Indian Journal of Microbiology. 55(4), 384-91. 
• Singh DK, Kumar A, Tiwari AK, Sankarasubramanian J, Vishnu US, Sridhar J, Gunasekaran P and Rajendhran J (2015) Draft genome sequence of Brucella abortus virulent strain 544. Genome Announcements. 3(3), e00419-15. 
• Sankarasubramanian J, Pavithra KB, Kavitha B (2015) Identification of Potent Inhibitor for RNA Dependent RNA polymerase (RDRP) of Dengue Virus Serotype-3: A Molecular Docking Study. Journal of Applied Bioinformatics & Computational Biology. 4, 1. 
• Sharma NS, Sunita T, Arora AK, Mudit C, Kaur P, Sankarasubramanian J, Vishnu US, Gunasekaran P, Rajendhran J (2015). Draft Genome Sequences of Two Brucella abortus Strains Isolated from Cattle and Pig. Journal of Genomics. 3, 95-96. 
• Vishnu US, Sankarasubramanian J, Gunasekaran P, Rajendhran J (2015) Novel Vaccine Candidates against Brucella melitensis Identified through Reverse Vaccinology Approach. OMICS: A Journal of Integrative Biology. 19(11), 722-9.
• Sankarasubramanian J, Vishnu U, Sridhar J, Gunasekaran P and Rajendhran J (2015) Pan-genome of Brucella species. Indian Journal of Microbiology. 55(1), 88–101. 
• Shome R, Krithiga N, Padmashree BS, Sankarasubramanian J, Vishnu US, Sridhar J, Gunasekaran P, Rajendhran J and Rahman H (2014) Draft genome sequence of Brucella abortus S99: designated antigenic smooth reference strain used in diagnostic tests in India. Genome Announcements. 2(4), e00824-14. 
• Shome R, Krithiga N, Muttannagouda RB, Veeregowda BM, Swati S, Shome BR, Vishnu U, Sankarasubramanian J, Sridhar J, Gunasekaran P, Rahman H, Rajendhran J (2013) Draft genome sequence of Brucella melitensis strain ADMAS-G1, isolated from placental fluids of an aborted goat. Genome Announcements. 1(5), e00809-13. 
• Jayashree S, Pooja S, Pushpanathan M, Vishnu U, Sankarasubramanian J, Rajendhran J, Gunasekaran P (2013) Genome sequence of Lactobacillus fermentum strain MTCC 8711, a probiotic bacterium isolated from yogurt. Genome Announcements. 1(5), e00770-13.

 

Abstract publications

• Chen W, Woods N, Hin Law H.C, Qiao F, Jagadesan S, Guda C, Bergan R.C.. Unveiling discordant views of a novel drug's influence on cell motility from proteomics and immunofluorescence perspectives [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4121. 
• Chen W, Woods N, Qiao F, Hin Law H.C, Jagadesan S, Guda C, Bergan R.C. (2023) Using bioinformatic analysis of proteomic data to probe novel drug mechanism of action [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl): Abstract nr 2028.