Dr. SANKARASUBRAMANIAN JAGADESAN

Skills in Research

• Data analysis in Single-cell RNA, Single-cell ATAC-seq, Single-cell CNV, Spatial transcriptome
• Next-generation sequencing and data analysis (Whole genome and RNAseq)
• Comparative genome analysis and metabolic modeling
• SNP analysis and Genome-wide association studies (GWAS)
• Metagenomics
• Microarray data analysis
• Interaction studies
• Docking and Structural studies
• Genome submission in NCBI (SRA & WGS)
• Explored and used various Bioinformatics tool.

Computational Skills

• Server management and maintenance (install OS, creating and configuring head node and nodes)
• Operating systems: Linux, Windows (installation and debugging the errors)
• Database development and maintenance (Proficient in HTML, CSS, PHP and MySQL)
• Biological Programming (R)
• Design & creative: Adobe Photoshop, Dreamweaver, CorelDraw and paint
• G Suite: Google Calendar, Docs, Drive, Forms, Gmail and Sheets
• Email: Gmail and Outlook • Microsoft Office 365: Word, Excel, PowerPoint, SharePoint and Teams
• Web browsers: Chrome, Firefox, Microsoft Edge, etc.
• Social media: ResearchGate, LinkedIn

Academic achievements

• Got best poster award on Genome-scale metabolic network reconstruction of Brucella abortus 2308. Poster in International conference on Brucellosis 2016 held at NASC complex, New Delhi on 16th – 19th November 2016. 
• Got 2nd prize in 3rd Annual Review Meet of “DBT-Network Project on Brucellosis” held on 19th-20th November 2015 at DRDO, Mysore. Title: Genomics of Brucella spp. 

Invited Talk

• Cambrionics Life Science, Chennai. December 26, 2021. Topic: Analysis of pathogenic microbes using various bioinformatics approaches. 
• Sage University, Bhopal. July 31, 2020. Topic: Bioinformatics and Genomics Approaches to Handle Infectious Disease.

Tools and database created

• VST-DAVis is deployed at: https://www.gudalab-rtools.net/VST-DAVis under the guidance of Dr. Guda, UNMC, Omaha, NE 
•  ScRDAVis is deployed at: https://www.gudalab-rtools.net/ScRDAVis under the guidance of Dr. Guda, UNMC, Omaha, NE 
• MetaDAVis is deployed at: https://www.gudalab-rtools.net/MetaDAVis under the guidance of Dr. Guda, UNMC, Omaha, NE 
• scAED is deployed at: https://www.gudalab-rtools.net/scAED under the guidance of Dr. Guda, UNMC, Omaha, NE  
• Created a database on “BrucellaBase: Genome Information Resource” under the guidance of Dr. J. Rajendran, Madurai Kamaraj University, Madurai. Available at: http://www.dbtbrucellosis.in/brucellabase.html 
• Created a database on “DBT-NETWOK PROJECT ON BRUCELLOSIS” under the guidance of Dr. J. Rajendran, Madurai Kamaraj University, Madurai. Available at: http://www.dbtbrucellosis.in 
• Created a project in “DATABASE ON INDIAN EARTHWORM” under the guidance of K.B.Pavithra, DBT-Bioinformatics Infrastructure Facility, Maharani Science College for women, Bangalore Available at: http://www.mscwbif.org/earthworm/home.html

Genome sequence submitted in NCBI

• ScRNA submitted to NCBI GEO - GSE242039 (15 Samples), GSE313588 (4 Samples)
• RNA-seq submitted to NCBI GEO: GSE157348 (24 samples), GSE159563 (18 samples), GSE236466 (12 samples), GSE290347 (24 samples)
• Whole genomes bacterial - 39 (SDWD00000000, SDWC00000000, SDWB00000000, SDWA00000000, SDVZ00000000, RZHS00000000, RZHT00000000, RZHU00000000, RZHV00000000, RZHW00000000, RZHX00000000, RZHY00000000, RZHZ00000000, RZIA00000000, RZIB00000000, QITZ00000000, QITY00000000, QITX00000000, QITW00000000, QITV00000000, QITU00000000, QITT00000000, QITS00000000, QITR00000000, QIUA00000000, JPHK00000000, JPHL00000000, JPHM00000000, LFJE00000000, MEHR00000000, LLKA00000000, MEDF00000000, LLVR00000000, NFUJ00000000, MVDZ00000000, MVDY00000000, MSZY00000000, AWTU00000000, AUTT00000000)
• Gene submitted in NCBI - 3 (MH790132, MH790131, MK027317)

Resource person during workshop

• Rajendhran J, Sankarasubramanian J, Vishnu US, Gunasekaran P. Workshop on Brucella Bioinformatics (18-22 December 2018) at Madurai Kamaraj University.
• Rajendhran J, Sankarasubramanian J, Vishnu US, Gunasekaran P. 32rd UGC-NRCBS Winter School on Functional & Integrative Genomics (18-31 January 2017) at Madurai Kamaraj University. 
• Rajendhran J, Sankarasubramanian J, Vishnu US, Gunasekaran P. 3rd Workshop on Brucella genomics (14-18 March 2016) at Madurai Kamaraj University. 
• Rajendhran J, Sridhar J, Gunasekaran P, Vishnu US, Sankarasubramanian J. 2nd Workshop on Brucella genomics (13-17 October 2014) at Madurai Kamaraj University. 
• Rajendhran J, Sridhar J, Gunasekaran P, Sankarasubramanian J, Vishnu US. Workshop on Brucella genomics (8-12 July 2013) at Madurai Kamaraj University.